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Innovation

Shifting Evolution Into Reverse Promises Cheaper, Greener Way to Make New Drugs

“Using bioretrosynthesis, it is theoretically possible to make almost any organic molecule out of simple sugars.”
This alternative approach to creating artificial organic molecules, called bioretrosynthesis, was first proposed four years ago by Brian Bachmann, associate professor of chemistry at Vanderbilt University. Now Bachmann and a team of collaborators report that they have succeeded in using the method to produce the HIV drug didanosine. The proof of concept experiment is described

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